Cell-based assays are reliable processes for research-based and commercial applications in the pharmaceutical and biotechnology sector, where the experiments are performed on live cells. The cellbased assays include a variety of assays that measure cell proliferation, toxicity, motility, production of a measurable product, and morphology, and range from cytotoxic assays to metabolic assays and cell proliferation. Cell-based assays also include the high throughput screening assays and other custom bioassays.

Vendors who fall into this category receive high scores for most of the evaluation criteria. They have a strong and established product portfolio and a very strong market presence. They provide mature, innovative, and reputable cell-based assay products.

The players considered as dynamic are established vendors with very strong business strategies. However, they provide limited offerings and are less innovative. They focus on a specific type of technology related to the product.

Innovators are vendors that have demonstrated substantial product innovations as compared to their competitors. They have a strong product portfolio, but lack a strong business strategy.

They are vendors with niche product offerings and are expected to gain a significant market position. They do not have developed business strategies as compared to other established vendors. Additionally, they might be new entrants in the market and require some time before gaining traction in the market.

Drug discovery involves the identification and validation of a drug and its action mechanism for the treatment of a specific disease. Cell-based assays are an essential tool in the drug discovery process, as they help streamline the process as well as reduce the overall cost and time involved. The cell-based assays are used to set a specific drug target. Biologically representative cell line and appropriate assay conditions are important for providing relevant results in drug discovery. With the increasing number of potential drug leads and targets, the use of cell-based assays in drug discovery processes is growing. Advantages of predictability, possibility of automation, multiplexing, and miniaturization of cell-based assays are driving their adoption in the drug discovery process, as they help provide effective results quickly. Cell-based assays are used in basic research for understanding the fundamental concepts of basic cellular functions and interactions between different cell types. These assays are extremely useful in predicting the cellular mechanisms and biological activities of compounds, which are considered important parameters in deducing the potential of a lead compound. ADME characterization is crucial during the process of drug development. ADME studies are aimed at measuring drug exposure and molecular kinetics and are typically carried out after lead optimization. They are becoming increasingly important to determine drug characteristics in the early stages, owing to the possibility of drug failure in clinical trials and the expenses associated with the process. In the ADME studies, to study the pharmacokinetics, a specific cell line is used, which leads to proper understanding of ADME of a drug.